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Indications for Use of Tramadol
Tramadol is indicated for the management of moderate to moderately severe pain. It is commonly prescribed for conditions such as:- Acute musculoskeletal pain
- Chronic musculoskeletal pain
- Postoperative pain
- Neuropathic pain
- Cancer pain
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Dosage and Administration
Tramadol is typically administered orally in the form of immediate-release tablets or extended-release formulations. The dosage prescribed depends on the severity of the pain, the individual's response to the medication, and other factors such as age, weight, and medical history. The usual starting dose for adults is 50 to 100 mg every 4 to 6 hours as needed for pain relief.Extended-release formulations of tramadol are designed to provide around-the-clock pain relief and are usually taken once daily. The dosage strengths of extended-release tramadol vary, but common doses include 100 mg, 200 mg, and 300 mg.
Adverse Effects
Tramadol is generally well-tolerated when used as directed, but like all medications, it can cause side effects. Common side effects of tramadol may include:- Nausea
- Dizziness
- Headache
- Constipation
- Drowsiness
- Dry mouth
- Sweating
- Seizures (particularly at higher doses or in individuals with a history of seizures)
- Serotonin syndrome (a potentially life-threatening condition characterized by agitation, hallucinations, rapid heartbeat, high blood pressure, fever, sweating, and tremors)
- Respiratory depression (especially when tramadol is taken in high doses or combined with other central nervous system depressants)