Casinos establish slot machine odds using game design, statistical mechanics, and random number generators (RNGs), which ensure each spin is independent. Key factors influencing these odds include the number of symbols, paylines, and the return to player (RTP) percentage, reflecting expected payouts over time. Common player misconceptions, such as attempting to forecast outcomes based on previous spins, believing higher denomination machines have better odds, and chasing losses, can lead to an underestimation of gambling risks.