Casinos calculate the odds of winning in roulette by taking into account the total number of possible outcomes on the wheel and the specific bets players can make. Each type of bet—such as betting on a single number, a color, or a range of numbers—has a different probability of winning based on the layout of the wheel, which includes numbers and, in American roulette, an additional 00 slot. The total number of pockets on the wheel determines the odds for each bet, while the design of the game ensures that the house edge is maintained, allowing the casino to profit over time.