Players who use card counting variations in Blackjack adapt to different game conditions and situations by adjusting their strategy, betting patterns, and count updates to maximize their expected value. They may switch between different card counting systems or methods depending on the specific game conditions, such as the number of decks, dealer's upcard, and betting limits. They may also adjust their betting patterns to take advantage of favorable or unfavorable conditions, such as increasing bets during periods of high expected value or reducing bets during periods of low expected value.