The house edge in Blackjack is calculated by comparing the odds of winning hands for the player versus the odds of winning for the casino. It takes into account the game's rules, such as the number of decks used, the payout for blackjack, and the dealer's rules for hitting and standing. Generally, the house edge is determined by analyzing the probabilities of various outcomes and the expected returns on bets. The result is often expressed as a percentage, indicating the casino's average profit from each bet placed over time. A lower house edge suggests a better chance for players to win in the long run.