Deciding whether to continue with a second-pair hand on the river depends on several factors, including the board texture, the size of the pot, and the actions of your opponents. If the river card improves the board in a way that could help you or your opponents, such as completing a potential straight or flush, you’ll need to assess whether your hand is still likely to be the best. If your opponents have been aggressive, particularly on earlier streets, they may have a stronger hand, making it less likely that second pair is good. You should also consider the pot odds you're getting to call, your opponent's range, and whether there’s a chance they could be bluffing. In some cases, second pair might be good enough to call a smaller bet, but in others, folding might be the wiser option.