Bluffing is most effective when you can credibly represent a strong hand, often on boards that favor your perceived range. The best opportunities arise when your opponent shows weakness, like checking multiple times or folding frequently to aggression. Bluffing is stronger when you have position, allowing you to see their reactions before committing. Consider the opponent’s tendencies—tight players are more likely to fold to pressure, while loose ones may call more often. The stage of the game matters too; early bluffs can build your image, but late-stage bluffs can have a greater impact when the stakes are higher. Effective bluffs balance risk and reward, aiming to exploit uncertainty.