When you have a flush draw on the turn with a large pot, your approach depends on the size of the pot, your position, and the actions of other players. If the pot is large and you're getting favorable odds, it's generally worth continuing to chase the draw, especially if you have the potential to win a significant amount if you hit your flush. You can call the bet to see the river card, considering whether the pot odds justify it. However, if you're facing a large bet and the pot odds are poor, you might need to fold or, if you’re in position, use a semi-bluff to apply pressure on opponents who may not have strong hands. In either case, be mindful of how much of your stack is at risk and how likely your draw is to hit on the river.