When playing Blackjack with a side bet like Perfect Pairs, you should stick to basic Blackjack strategy for the main game, focusing on decisions like hitting, standing, and doubling down. However, you’ll need to adjust for the higher house edge on the Perfect Pairs side bet, which typically ranges around 5-6%. To mitigate this, keep your side bet smaller—usually about 1/4 to 1/2 of your main bet. While the potential payouts for Perfect Pairs can be appealing, they come with a higher risk, and it’s generally recommended to focus on the core Blackjack strategy for maximizing long-term success. If you do choose to bet on Perfect Pairs, it’s important to manage your bankroll wisely and avoid relying too heavily on side bets.