Draws in PLO should be played aggressively when they have strong equity, especially in multi-way pots. Nut draws, such as the nut flush or wrap straight draws, are often semi-bluffed to apply pressure and build the pot. Weak draws, particularly non-nut flushes or gutshots, should be played cautiously to avoid domination. Position is crucial, as it allows for better decision-making based on opponents’ actions.