Playing out of position requires a cautious and adaptable approach. It often involves tighter hand selection to compensate for the disadvantage of acting first. Controlling the pot size is crucial, as larger bets can leave you vulnerable when you lack information about your opponent's actions. Using defensive play, like check-calling or small probing bets, helps manage the risk while gathering information. Bluffing should be selective and credible, as opponents tend to scrutinize more closely. A mix of aggression and control helps offset the positional disadvantage and minimizes losses when uncertain.