Deciding when to fold pre-flop involves assessing several factors, including hand strength, table position, and the style of play of your opponents. A weak or marginal hand, especially from an early position, is often a fold unless the table is particularly passive. Player tendencies also matter; if there are aggressive players left to act, folding weaker hands can avoid difficult spots. Pot odds and stack sizes also play a role, as speculative hands might not be worth it if the implied odds aren’t favorable. Ultimately, it’s about balancing the risks and potential rewards based on your situation at the table.