In Blackjack, the cards from 2 through 10 hold their face value, while face cards (King, Queen, and Jack) are each worth 10. Aces can be worth either 1 or 11, depending on which benefits the hand more. These values impact the game by influencing strategy, as players aim to reach a hand total of 21 without exceeding it. The flexibility of the Ace plays a key role in adjusting hand totals, while high-value cards like 10s and face cards increase the chances of reaching 21 but also the risk of busting.