The difference between various roulette software platforms primarily lies in their game variety, graphics quality, user interface, and features. Some platforms may offer traditional European, American, and French Roulette, while others include unique variations and themed games. Additionally, the level of realism and interactivity can differ, with some platforms providing advanced graphics and animations or live dealer options. Software reliability, speed of gameplay, and compatibility with mobile devices also vary, impacting the overall player experience.