The house edge in blackjack typically ranges from 0.5% to 2%, depending on the rules and strategy. To minimize it, use basic strategy, which helps reduce the house edge to around 0.5%. Additionally, employing card counting can further reduce the advantage or even give you an edge. Playing at tables with favorable rules, such as 3:2 blackjack payouts and options to double down, also helps lower the house edge. While the edge can never be completely eliminated, these strategies can significantly minimize it.