Following sharp money can be advantageous when significant line movements indicate that knowledgeable bettors are placing large wagers, suggesting a likely mispricing by the sportsbooks. This can be particularly effective in situations where public opinion heavily sways the odds, creating value in the opposite direction. However, going against perceived smart money might be worthwhile when the line moves contradicts sound reasoning or analytics, or when the sharp money is based on incomplete information or biases that the public may not have considered.