Knowing when to walk away from a machine is about recognizing signs that it might be wise to stop playing. Key indicators include reaching a predetermined loss limit, feeling frustrated or emotional, or consistently losing over a period of time, which suggests that luck isn't on your side. Additionally, if playing ceases to be enjoyable and becomes stressful, it's best to take a break or exit. Setting clear personal boundaries before starting can help reinforce the decision to walk away at the right moment, ensuring a responsible and enjoyable gaming experience.