The casino with the most roulette tables is typically the Casino de Monte-Carlo in Monaco, one of the most iconic and historically significant casinos in the world. However, large casinos in Las Vegas, such as The Venetian and Caesars Palace, are known for having a substantial number of roulette tables as well. The exact number of roulette tables can vary, but major casinos in high-traffic gambling destinations like Monte-Carlo, Las Vegas, and Macau generally have dozens of tables to accommodate the demand for the game, offering a wide variety of roulette variants.