The regulation of online gambling varies significantly across regions. In Latin America, Colombia leads with a comprehensive framework for online sports betting, while Argentina has decentralized its regulation by province. Chile and Brazil are still in the early stages of adopting laws, while in the US, state-level regulations are more common following the 2018 Supreme Court decision. Europe has more established systems, with Spain and Italy enforcing tax and licensing measures, while the UK is revising its laws to address gambling addiction prevention.